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Publications

2013

  1. Dhammika Weerakkody, Anna Moshnikova, Mak S. Thakur, Valentina Moshnikova, Jennifer Daniels, Donald M. Engelman, Oleg A. Andreev, and Yana K. Reshetnyak, “Family of pH (low) insertion peptides for tumor targeting,” PNAS, Vol 110, No. 15 pp. 5834-5839, 2013.
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  2. Lan Yao, Jennifer Daniels, Dayanjali Wijesinghe, Oleg A. Andreev, Yana K. Reshetnyak, “pHLIP Mediated Delivery of PEGylated Liuposomes to Cancer Cells,” Journal of Controlled Release, Vol 167, pp. 228-237, 2013.
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  3. Anna Moshnikova, Valentina Moshnikova, Oleg A. Andreev, Yana K. Reshetnyak, “Antiproliferative Effect of pHLIP-Amanitin,” Biochemistry, Vol 57, No. 7, pp. 1171-1178, 2013.
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  4. Eugene A. Sosunova, Evgeny P. Anyukhovsky, Alexander A. Sosunov, Anna Moshnikova, Dayanjali Wijesinghe, Donald M. Engelmand, Yana K. Reshetnyak, and Oleg A. Andreev, “pH (low) insertion peptide (pHLIP) targets ischemic myocardium,” PNAS, Vol 110, No. 1, pp. 82-86, 2013.
    [PDF]

  5. Lan Yao, Jennifer Danniels, Anna Moshnikova, Sergey Kuznetsov, Aftab Ahmed, Donald M. Engelman, Yana K. Reshetnyak, and Oleg A. Andreev, “pHLIP peptide targets nanogold particles to tumors,” PNAS, Vol 110, No. 2, pp. 465-470, 2013.
    [PDF]

2012

  1. Yana K. Reshetnyak, Cynthia N. Prudence, James Segala, Vladislav S. Markin, Oleg A. Andreev, “Parking problem and negative cooperativity of binding of myosin subfragment 1 to F-actin,” Biochemical and Biophysical Research Communications, Vol. 425, pp. 476-479, 2012.
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  2. Pierre Daumar, Cindy Wanger-Baumann, Nagavara Pillarsetty, Laura A Fabrizio, Sean D Carlin, Yana K. Reshetnyak, Oleg A. Andreev, and Jason S. Lewis, “Efficient [18F]-Labeling of Large 37-Amino Acid pHLIP Peptide Analogues and their Biological Evaluation,” Bioconjugate Chemistry, pp. 1-45, 2012.
    [PDF]

  3. Alexander G. Karabadzhak, Dhammika Weerakkody, Dayanjali Wijesinghe, Mak S. Thakur, Donald M. Engelman, Oleg A. Andreev, Vladislav S. Markin, and Yana K. Reshetnyak, “Modulation of the pHLIP Transmembrane Helix Insertion Pathway,” Biophysical Journal, vol. 102, pp. 1846-1855, 2012.
    [PDF]

  4. Sven Macholl, Matthew S. Morrison, Peter Iveson, Bente E. Arbo, Oleg A. Andreev, Yana K. Reshetnyak, Donald M. Engelman, Edvin Johannesen, “In Vivo pH Imaging with 99mTc-pHLIP,” Molecular Imaging Biology, vol. 14, pp. 725-734, 2012.
    [PDF]

2011

  1. Francisco N. Barrera, Dhammika Weerakkody, Michael Anderson, Oleg A. Andreev, Yana K. Reshetnyak and Donald M. Engelman, "Roles of Carboxyl Groups in the Transmembrane Insertion of Peptides," Journal of Molecular Biology, vol. 413, pp. 359-371, 2011.
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  2. Y. K. Reshetnyak, L. Yao, S. Zheng, S. Kuznetsov, D. M. Engelman and O. A. Andreev, "Measuring Tumor Aggressiveness and Targeting Metastatic Lesions with Fluorescent pHLIP," Mol Imaging Biol, vol. 13, pp. 1146-1156, 2011.
    [PDF]

  3. Dayanjali Wijesinghe, Donald M. Engelman, Oleg A. Andreev, and Yana K. Reshetnyak, "Tuning a Polar Molecule for Selective Cytoplasmic Delivery by a pH(Low) Insertion Peptide," Biochemistry, vol. 50, pp. 10215-10222, 2011.
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  4. Cynthia N. Prudence, Brad Boudreau, Yana K. Reshetnyak, "Protein Fluorescence Database," Recent Researches in Chemistry, Biology, Environment and Culture, pp. 59-63, 2011.
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2010

  1. M. An, D. Wijesinghe, O. A. Andreev, Y. K. Reshetnyak and D. M. Engelman, "pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation," Proc Natl Acad Sci U S A, vol. 107, no. 47, pp. 20246-50, 2010.
    [PDF]

  2. O. A. Andreev, A. G. Karabadzhak, D. Weerakkody, G. O. Andreev, D. M. Engelman and Y. K. Reshetnyak, "pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path," Proc Natl Acad Sci U S A, vol. 107, no. 9, pp. 4081-6, 2010.
    [PDF]

  3. O. A. Andreev, D. M. Engelman and Y. K. Reshetnyak, "pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents," Mol Membr Biol, vol. 27, no. 7, pp. 341-52, 2010.
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  4. M. Musial-Siwek, A. Karabadzhak, O. A. Andreev, Y. K. Reshetnyak and D. M. Engelman, "Tuning the insertion properties of pHLIP," Biochim Biophys Acta, vol. 1798, no. 6, pp. 1041-6, 2010.
    [PDF]

  5. L. Yao, J. Segala, A.J. Bucci, G.O. Andreev, Y.K. Reshetnyak, and O.A. Andreev, "Fluorescence anistrophy imaging microscopy," Microscopy: Science, Technology, Applications and Education, Formatex Research Center, 3, pp. 2072-8, 2010.
    [PDF]

2009

  1. O. A. Andreev, D. M. Engelman and Y. K. Reshetnyak, "Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP)," Chemistry Today, vol. 27, no. 2, pp. 34-37, 2009.
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  2. J. Hixon, and Y. K. Reshetnyak, "Algorithm for the Analysis of Tryptophan Fluorescence Spectra and Their Correlation with Protein Structural Parameters," Algorithms, vol. 2, pp. 1155-76, 2009.
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  3. J. Segala, D. M. Engelman, Y. K. Reshetnyak and O. A. Andreev, "Accurate analysis of tumor margins using a fluorescent pH Low Insertion Peptide (pHLIP)," Int J Mol Sci, vol. 10, no. 8, pp. 3478-87, 2009.
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  4. A. L. Vavere, G. B. Biddlecombe, W. M. Spees, J. R. Garbow, D. Wijesinghe, O. A. Andreev, D. M. Engelman, Y. K. Reshetnyak and J. S. Lewis, "A novel technology for the imaging of acidic prostate tumors by positron emission tomography," Cancer Res, vol. 69, no. 10, pp. 4510-6, 2009.
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  5. L. Yao, G. O. Andreev, Y. K. Reshetnyak and O. A. Andreev, "Fabrication of semiconductor nanowires by conjugation of quantum dots to actin filaments," Anal Bioanal Chem, vol. 395, no. 5, pp. 1563-6, 2009.
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2008

  1. N. Jain, Y. K. Reshetnyak, L. Gao, M. P. Chiarelli and B. P. Cho, "Fluorescence probing of aminofluorene-induced conformational heterogeneity in DNA duplexes," Chem Res Toxicol, vol. 21, no. 2, pp. 445-52, 2008.
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  2. Y. K. Reshetnyak, O. A. Andreev, M. Segala, V. S. Markin and D. M. Engelman, "Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane," Proc Natl Acad Sci U S A, vol. 105, no. 40, pp. 15340-5, 2008.
    [PDF]

  3. C. Shen, R. Menon, D. Das, N. Bansal, N. Nahar, N. Guduru, S. Jaegle, J. Peckham and Y. K. Reshetnyak, "The protein fluorescence and structural toolkit: Database and programs for the analysis of protein fluorescence and structural data," Proteins, vol. 71, no. 4, pp. 1744-54, 2008.
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  4. M. Zoonens, Y. K. Reshetnyak and D. M. Engelman, "Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumors," Biophys J, vol. 95, no. 1, pp. 225-35, 2008.
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2007

  1. O. A. Andreev, A. D. Dupuy, M. Segala, S. Sandugu, D. A. Serra, C. O. Chichester, D. M. Engelman and Y. K. Reshetnyak, "Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo," Proc Natl Acad Sci U S A, vol. 104, no. 19, pp. 7893-8, 2007.
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  2. O. A. Andreev and Y. K. Reshetnyak, "Mechanism of formation of actomyosin interface," J Mol Biol, vol. 365, no. 3, pp. 551-4, 2007.
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  3. Y. K. Reshetnyak, M. Segala, O. A. Andreev and D. M. Engelman, "A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers," Biophys J, vol. 93, no. 7, pp. 2363-72, 2007.
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  4. M. Torrent, E. Cuyas, E. Carreras, S. Navarro, O. Lopez, A. de la Maza, M. V. Nogues, Y. K. Reshetnyak and E. Boix, "Topography studies on the membrane interaction mechanism of the eosinophil cationic protein," Biochemistry, vol. 46, no. 3, pp. 720-33, 2007.
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2006

  1. O. A. Andreev, S. Sandugu, D. M. Engelman, and Y. K. Reshetnyak "Injection of Molecules into cells using a pH-triggered molecular nanosyringe," Technical Proceed. of the 2006 Nanotech Conf., vol. 2, pp. 57-60, 2006.
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  2. Y. K. Reshetnyak, O. A. Andreev, U. Lehnert and D. M. Engelman, "Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix," Proc Natl Acad Sci U S A, vol. 103, no. 17, pp. 6460-5, 2006.
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  3. Y. Reshetnyak, K. T. Tchedre, M. P. Nair, P. H. Pritchard and A. G. Lacko, "Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase," J Biomol Struct Dyn, vol. 24, no. 1, pp. 75-82, 2006.
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2004

  1. D. Linke, J. Frank, M. S. Pope, J. Soll, I. Ilkavets, P. Fromme, E. A. Burstein, and Y. Reshetnyak, "Folding Kinetics and Structure of OEP16," Biophys.J., vol. 86, no. 3, pp. 1479-1487, 2004.
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  2. Y.K. Reshetnyak, R. P. Kitson, M. Lu, and R. H. Goldfarb, "Conformational and enzymatic changes of 20S proteasome of rat natural killer cells induced by mono and divalent cations," J. Struct. Biol., vol. 145, no. 3, pp. 263-71, 2004.
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2003

  1. D. M. Engelman, Y. Chen, C. N. Chin, A. R. Curran, A. M. Dixon, A. D. Dupuy, A. S. Lee, U. Lehnert, E. E. Matthews, Y. K. Reshetnyak, A. Senes and J. L. Popot, "Membrane protein folding: beyond the two stage model," FEBS Lett, vol. 555, no. 1, pp. 122-5, 2003
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  2. N.Ya Orlov, Y.K. Reshetnyak, T.G. Orlova, D.N. Orlov, Burstein E.A.,Y. Ishijima, and N. Kimura, "Protein fluorescence study of chimeras and tagged forms of recombinant rat nucleoside diphosphate kinases alpha and beta," Biological Membranes(Moscow), vol. 20, no. 1, pp. 53-59, 2003
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2002

  1. O. A. Andreev, Y. K. Reshetnyak and R. H. Goldfarb, "Evidence of inter- and intra-molecular crosslinking of tyrosine residues of calmodulin induced by photo-activation of ruthenium(II)," Photochem Photobiol Sci, vol. 1, no. 10, pp. 834-6, 2002.
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2001

  1. J. Borejdo, D. S. Ushakov, R. Moreland, I. Akopova, Y. Reshetnyak, L. D. Saraswat, K. Kamm and S. Lowey, "The power stroke causes changes in the orientation and mobility of the termini of essential light chain 1 of myosin," Biochemistry, vol. 40, no. 13, pp. 3796-803, 2001.
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  2. E. A. Burstein, S. M. Abornev and Y. K. Reshetnyak, "Decomposition of protein tryptophan fluorescence spectra into log-normal components. I. Decomposition algorithms," Biophys J, vol. 81, no. 3, pp. 1699-709, 2001.
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  3. Y. K. Reshetnyak and E. A. Burstein, "Decomposition of protein tryptophan fluorescence spectra into log-normal components. II. The statistical proof of discreteness of tryptophan classes in proteins," Biophys J, vol. 81, no. 3, pp. 1710-34, 2001.
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  4. Y. K. Reshetnyak, Yuly Koshevnik and E. A. Burstein, "Decomposition of protein tryptophan fluorescence spectra into log-normal components: III. Correlation between fluorescence and microenvironment parameters of individual tryptophan residues," Biophys J, vol. 81, no. 3, pp. 1735-58, 2001.
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  5. Y. K. Reshetnyak and O. A. Andreev, "The interdomain motions in myosin subfragment 1," Biophys Chem, vol. 94, no. 1-2, pp. 41-6, 2001.
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  6. L.K. Skrebnitskaia, G.N. Vishniakov, S.A. Neiman, Z.E. Rozhdestvenskaia, O.A. Andreev, & G.G.Levin, "Two-dimensional reconstruction of birefringence map of the skeletal muscle sarcomere in relaxed and rigor states studied by interference microscopy," Biophysics (Moscow), vol. 46, pp. 518-523, 2001.
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2000

  1. V. I. Emel'ianenko, Ya.K. Reshetniak, O. A. Andreev and E. A. Burshtein, "[Analysis of log-normal components of fluorescence spectra of prodan and acrylodan bound to proteins]," Biofizika, vol. 45, no. 2, pp. 207-19, 2000.
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  2. Y. K. Reshetnyak, O. A. Andreev, J. Borejdo, D. D. Toptygin, L. Brand and E. A. Burstein, "The identification of tryptophan residues responsible for ATP-induced increase in intrinsic fluorescence of myosin subfragment 1," J Biomol Struct Dyn, vol. 18, no. 1, pp. 113-25, 2000.
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1999

  1. O. A. Andreev and J. Borejdo, "Binding of myosin cross-bridges to thin filaments of rabbit skeletal muscle," Biochem Biophys Res Commun, vol. 258, no. 3, pp. 628-31, 1999.
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  2. O. A. Andreev, L. D. Saraswat, S. Lowey, C. Slaughter and J. Borejdo, "Interaction of the N-terminus of chicken skeletal essential light chain 1 with F-actin," Biochemistry, vol. 38, no. 8, pp. 2480-5, 1999.
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  3. N. Y. Orlov, T. G. Orlova, Y. K. Reshetnyak, E. A. Burstein and N. Kimura, "Comparative study of recombinant rat nucleoside diphosphate kinases alpha and beta by intrinsic protein fluorescence," J Biomol Struct Dyn, vol. 16, no. 4, pp. 955-68, 1999.

1998

  1. O. A. Andreev, D. S. Ushakov and J. Borejdo, "Effect of ADP on binding of skeletal S1 to F-actin," Biochemistry, vol. 37, no. 51, pp. 17836-42, 1998.
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1997

  1. O. A. Andreev and J. Borejdo, "Interaction of the heavy and light chains of cardiac myosin subfragment-1 with F-actin," Circ Res, vol. 81, no. 5, pp. 688-93, 1997.
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  2. N. Orlov, T. G. Orlova, Y. K. Reshetnyak, E. A. Burstein and N. Kimura, "Interaction of recombinant rat nucleoside diphosphate kinase alpha with bleached bovine retinal rod outer segment membranes: a possible mode of pH and salt effects," Biochem Mol Biol Int, vol. 41, no. 1, pp. 189-98, 1997.
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  3. Ya.K Reshetnyak and E.A. Burstein, "Assignment of log-normal components of fluorescence spectra of serine proteases to the clusters of tryptophan residues," Molecular Biophysics, vol. 42, no. 4, pp. 785-95, 1997.
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  4. Ya.K Reshetnyak and E.A. Burstein, "Assignment of log-normal components of protein fluorescence spectra to individual tryptophan residues using their microenvironment properties in three-dimensional structure," Molecular Biophysics, vol. 42, no. 2, pp. 293-300, 1997.
    [PDF]

1996

  1. M. Xiao, A. Tartakowski, O. A. Andreev and J. Borejdo, "Binding of S1(A1) and S1(A2) to F-actin," Biochemistry, vol. 35, no. 2, pp. 523-30, 1996.
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1995

  1. O. A. Andreev and J. Borejdo, "Binding of heavy-chain and essential light-chain 1 of S1 to actin depends on the degree of saturation of F-actin filaments with S1," Biochemistry, vol. 34, no. 45, pp. 14829-33, 1995.
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  2. O. A. Andreev, R. Takashi and J. Borejdo, "Fluorescence polarization study of the rigor complexes formed at different degrees of saturation of actin filaments with myosin subfragment-1," J Muscle Res Cell Motil, vol. 16, no. 4, pp. 353-67, 1995.
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  3. N.V. Karsanov, G.V. Sukoyan, E.B. Yarovaya, Z.N. Karsanov, Z.G. Khugashvili, D.R. Tatulashvili, T.G. Samsonidze, V.M. Pirskhalaishvili, Y. K. Reshetnyak, I.I. Goreliashvili, and N.N. Kipshidze, "Subcellular basis of the myocardial contractile activity disturbance in acute alcoholic intoxication," Questions of Narcology (Moscow), vol. 3, pp. 36-41, 1995.

  4. N.V. Karsanov, G.V. Sukoyan, D.R. Tatulashvili, E.B. Yarovaya, T.G. Samsonidze, Z.N. Karsanov, E.I. Guchua, Z.G. Khugashvili, Y. K. Reshetnyak, V.M. Pirskhalaishvili, I.I. Goreliashvili, and N.N. Kipshidze, "ubcellular basis of the myocardial contractile activity disturbance in the dynamic of alcoholic damage development," Questions of Narcology (Moscow), vol. 4, pp. 48-52, 1995.

  5. M. Xiao, O. A. Andreev and J. Borejdo, "Rigor cross-bridges bind to two actin monomers in thin filaments of rabbit psoas muscle," J Mol Biol, vol. 248, no. 2, pp. 294-307, 1995.
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1993

  1. O. A. Andreev, A. L. Andreeva and J. Borejdo, "Polarization of fluorescently labeled myosin subfragment-1 fully or partially decorating muscle fibers and myofibrils," Biophys J, vol. 65, no. 3, pp. 1027-38, 1993.
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  2. O. A. Andreev, A. L. Andreeva, V. S. Markin and J. Borejdo, "Two different rigor complexes of myosin subfragment 1 and actin," Biochemistry, vol. 32, no. 45, pp. 12046-53, 1993.
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  3. A. L. Andreeva, O. A. Andreev and J. Borejdo, "Structure of the 265-kilodalton complex formed upon EDC cross-linking of subfragment 1 to F-actin," Biochemistry, vol. 32, no. 50, pp. 13956-60, 1993.

1992

  1. O. A. Andreev and J. Borejdo, "Two different acto-S1 complexes," J Muscle Res Cell Motil, vol. 13, no. 5, pp. 523-33, 1992.
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  2. O. Andreev and J. Borejdo, "Binding of myosin subfragment-1 to F-actin," Biochem Biophys Res Commun, vol. 188, no. 1, pp. 94-101, 1992.
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1991

  1. O. A. Andreev and J. Borejdo, "The myosin head can bind two actin monomers," Biochem Biophys Res Commun, vol. 177, no. 1, pp. 350-6, 1991.
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1989

  1. O. A. Andreev, S.N. Udaltsov, Z.E. Rogdestvenskaya, and V.V. Lednev, "Anisotropy of tryptophan fluorescence of glycerinated muscle fibers," Biophysica, vol. 134, pp. 249-56, 1989.

  2. O. A. Andreev, Z.E. Rogdestvenskaya, S.N. Udaltsov, and V.V. Lednev, "Anisotropy of intrinsic fluorescence of glycerinated muscle fibers of rabbit in relax and in rigor states. ," Biophysics (Moscow), vol. 34, pp. 327-9, 1989.

1984

  1. O. A. Andreev, "Fluorescence polarization microscope with electro optical intensifier," Automatization of biotechnological processes and biological experiments, Varna, Bulgaria, pp. 375-379, 1984.
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1982

  1. A. A. Klimov and O. A. Andreev, "Accuracy of determining sarcomere lengths in contracted muscle by laser diffraction method," Biofizika, vol. 27, no. 1, pp. 111-3, 1982.
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